What category do drugs with the highest potential for abuse and no accepted medical use fall under?

Drugs that fall under Schedule I are classified as having the highest potential for abuse and no accepted medical use in the United States. This category includes substances that are deemed unsafe for use even under medical supervision, which means they cannot legally be prescribed. Examples of Schedule I drugs include heroin and lysergic acid diethylamide (LSD). This classification reflects a significant concern about the risk of addiction and the lack of accepted therapeutic benefits, leading to stringent regulations surrounding their possession and use. Conversely, the other schedules encompass substances with varying degrees of medical acceptance and potential for abuse.